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The combination of a novel blood test and magnetic resonance imaging (MRI) can reduce overdiagnosis of low-risk cancers as well as societal costs in prostate cancer screening, according to a cost-effectiveness study from Karolinska Institutet published in the journal European Urology. The results provide support for organised prostate cancer testing in Sweden, researchers say. A […]
Results from an international, randomized, double-blind, placebo-controlled, phase 3 clinical trial indicate that adding the androgen-receptor inhibitor darolutamide to androgen-deprivation therapy and chemotherapy prolongs the survival of men with metastatic, hormone-sensitive prostate cancer, a disease that is fatal in most cases. The study, which was conducted by a team led by investigators at Massachusetts General
An ultrasound scan can be used to detect cases of prostate cancer, according to new research. Researchers at Imperial College London, University College London and Imperial College Healthcare NHS Trust have found that a new type of ultrasound scan can diagnose most prostate cancer cases with good accuracy in a clinical trial involving 370 men.
Ultrasound scan can diagnose prostate cancer Read More »
Calculating a person’s risk of developing prostate cancer using results from two blood markers would improve the accuracy of screening for the disease, reports a new study led by a UCL researcher. Prostate cancer is the most common form of cancer in men, with more than 10,000 men dying from the disease every year in
New risk algorithm would improve screening for prostate cancer Read More »
A new study from Keck Medicine of USC finds that the incidence rate of metastatic prostate cancer has significantly increased for men 45 and older and coincides with recommendations against routine prostate cancer screenings. “This study is the first to document a continued rise in metastatic prostate cancer using the most up-to-date population dataset,” said
Metastatic prostate cancer on the rise since decrease in cancer screenings Read More »
Prostate cancers remain localised in the majority of cases, giving affected individuals a good chance of survival. However, about 20% of patients develop incurable metastatic prostate cancer, resulting in approximately 5,000 deaths each year in Austria alone. Medical research has not yet adequately explained why metastases occur in some people and not in others. A
Cause of metastasis in prostate cancer discovered Read More »
Licorice is more than a candy people either love or hate — it may play a role in preventing or treating certain types of cancer, according to researchers at the University of Illinois Chicago. Gnanasekar Munirathinam and his research team are studying substances derived from the licorice plant Glycyrrhiza glabra to determine if they could
Researchers look to licorice for promising cancer treatments Read More »
Researchers have found that treating prostate cancer cells with novel cyclin-dependent kinase 19 (CDK19) and homologous cyclin-dependent kinase 8 (CDK8) inhibitors reduces their potential to migrate into and invade surrounding structures. These molecules may be used as single or combination therapy for patients with advanced disease to prevent and treat metastatic spread. The results appear
Novel therapeutic agents may reduce the oncogenesis of metastatic prostate cancer Read More »
Over the past 15 years, public health authorities have downgraded recommendations for the prostate-specific antigen (PSA) test as a screening tool to reduce the overdiagnosis and overtreatment of men with low-grade prostate cancer. Now, researchers from Weill Cornell Medicine have found that while these efforts have been effective, the incidence of higher-grade disease and metastasis
Less prostate cancer screening reduces overdiagnosis but may miss aggressive cases Read More »
Hormone therapy is often used to treat prostate cancer that has spread to other parts of the body, but many patients develop resistance to hormone therapy, causing their disease to become more aggressive and potentially more deadly. “One of the big challenges we have in the field is that the majority of prostate cancer therapies
How tumor cells use mitochondria to keep growing Read More »
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