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aortic ruptures

Detecting, predicting, and preventing aortic ruptures with computational modeling

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An abdominal aortic aneurysm (AAA) causes the wall of a person’s aorta, the largest artery in the body, to weaken and bulge outward. If left untreated, it can continue to grow and eventually rupture, which can lead to life-threatening bleeding. According to some estimates, up to 80% of patients who experience a ruptured AAA will […]

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Boosting the body's anti-viral immune response may eliminate aging cells

Boosting the body's anti-viral immune response may eliminate aging cells

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Aging, or senescent cells, which stop dividing but don’t die, can accumulate in the body over the years and fuel chronic inflammation that contributes to conditions such as cancer and degenerative disorders. In mice, eliminating senescent cells from aging tissues can restore tissue balance and lead to an increased healthy lifespan. Now a team led

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prostate cancer treatment

Research suggests commonly used prostate cancer treatment rewires engine of prostate tumors

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Drugs like enzalutamide that inhibit male hormones from activating the androgen receptor have been used to treat advanced prostate cancer for more than a decade. While successful in most cases, these drugs can eventually stop working, but there is a limited understanding about how this change occurs. A new study from the University of Michigan

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fight the aging process

Researchers discover a way to fight the aging process and cancer development

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A protein complex prevents the repair of genome damage in human cells, in mice and in the nematode Caenorhabditis elegans, a team of researchers at the University of Cologne has discovered. They also successfully inhibited this complex for the first time using a pharmaceutical agent. “When we suppress the so-called DREAM complex in body cells,

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Children at risk of multiple sclerosis often go undetected in early stages

Children at risk of multiple sclerosis often go undetected in early stages

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Criteria used by neurologists to assess for multiple sclerosis (MS) in adults may fail to identify the illness in children with imaging suspicious for the disease, an oversight that could delay treatment of the disease at its earliest stages, according to a Rutgers study. Magnetic resonance imaging (MRI) is the primary tool used for diagnosis

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Planaria flatworms can be alternative screening tool to avoid rabbit skin testing

Planaria flatworms can be alternative screening tool to avoid rabbit skin testing

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Tests for skin treatments could be screened using flatworms rather than other animals such as rabbits, according to new research. A team at the University of Reading and Newcastle University have found that planaria, a type of flatworm, can be used as a reliable alternative for testing topical skin products used to treat human tissues

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A new combination therapy regimen shows promising results for prostate cancer

A new combination therapy regimen shows promising results for prostate cancer

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TALAPRO-2, a study led by Neeraj Agarwal, MD, FASCO demonstrated that using TALZENNA, in combination with XTANDI, may reduce the risk of disease progression or death by 37%. Agarwal, Presidential Endowed Chair of Cancer Research at Huntsman Cancer Institute, presented the results of one of his many Phase III trials at the American Society of

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psychiatric disorders

Telomere shortening — a sign of cellular aging — linked to signs of Alzheimer's in brain scans

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Changes in the brain caused by Alzheimer’s disease are associated with shortening of the telomeres — the protective caps on the ends of chromosomes that shorten as cells age — according to a new study led by Anya Topiwala of Oxford Population Health, part of the University of Oxford, UK, published March 22 in the

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tumors

Lighting up tumors could help surgeons remove them more precisely

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A new technique that combines highly detailed, real-time images of inside the body with a type of infrared light has, for the first time, been used during surgery to differentiate between cancerous tumours and healthy tissue. The pioneering technique, demonstrated in mice, has been developed by engineers at the Wellcome/EPSRC Centre for Interventional and Surgical

Lighting up tumors could help surgeons remove them more precisely Read More »

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