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Prostate cancers remain localised in the majority of cases, giving affected individuals a good chance of survival. However, about 20% of patients develop incurable metastatic prostate cancer, resulting in approximately 5,000 deaths each year in Austria alone. Medical research has not yet adequately explained why metastases occur in some people and not in others. A […]
Cause of metastasis in prostate cancer discovered Read More »
Licorice is more than a candy people either love or hate — it may play a role in preventing or treating certain types of cancer, according to researchers at the University of Illinois Chicago. Gnanasekar Munirathinam and his research team are studying substances derived from the licorice plant Glycyrrhiza glabra to determine if they could
Researchers look to licorice for promising cancer treatments Read More »
Researchers have found that treating prostate cancer cells with novel cyclin-dependent kinase 19 (CDK19) and homologous cyclin-dependent kinase 8 (CDK8) inhibitors reduces their potential to migrate into and invade surrounding structures. These molecules may be used as single or combination therapy for patients with advanced disease to prevent and treat metastatic spread. The results appear
Novel therapeutic agents may reduce the oncogenesis of metastatic prostate cancer Read More »
Over the past 15 years, public health authorities have downgraded recommendations for the prostate-specific antigen (PSA) test as a screening tool to reduce the overdiagnosis and overtreatment of men with low-grade prostate cancer. Now, researchers from Weill Cornell Medicine have found that while these efforts have been effective, the incidence of higher-grade disease and metastasis
Less prostate cancer screening reduces overdiagnosis but may miss aggressive cases Read More »
Hormone therapy is often used to treat prostate cancer that has spread to other parts of the body, but many patients develop resistance to hormone therapy, causing their disease to become more aggressive and potentially more deadly. “One of the big challenges we have in the field is that the majority of prostate cancer therapies
How tumor cells use mitochondria to keep growing Read More »
Practice-changing research from Cedars-Sinai Cancer shows that a combination of androgen deprivation therapy — a commonly used hormone injection — plus pelvic lymph node radiation, kept nearly 90% of clinical trial patients’ prostate cancer at bay for five years. The findings were published in the peer-reviewed journal The Lancet. The study also shows that patients
New combined therapy helps extend lives of men with prostate cancer Read More »
Researchers at Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center have identified a previously unrecognized form of hormone therapy-resistant prostate cancer, as well as a set of molecules that drive its growth. This discovery opens the door to the development of therapies that treat this specific disease. In the study, published May 27 in
New cancer subtype may illuminate treatment strategy Read More »
Male sex hormones interfere with the body’s ability to fight bladder cancer, likely explaining why males experience higher cancer rates and more deadly disease, according to a new study co-led by a Cedars-Sinai Cancer investigator. These findings, published in Science Immunology, could represent a significant step toward unraveling why disparities in cancer incidence, prognosis and
Hormones contribute to sex disparities in bladder cancer, study shows Read More »
We are pursuing the dream of eternal life. We fast to stay healthy. And each year, we spend billions of kroner on treatment to make sure we stay alive. But some people turn 100 years old all by themselves. Why is that? Researchers from the Novo Nordisk Foundation Center for Protein Research at the University
Why do some people live to be 100? Intestinal bacteria may hold the answer Read More »
A new highly selective PET imaging agent can detect the presence of overexpressed monoamine oxidase-B (MAO-B) in cognitively unimpaired individuals with high beta amyloid (Ab) — one of the earliest signs of Alzheimer’s disease — according to research published in the October issue of The Journal of Nuclear Medicine. The radiotracer, 18F-SMBT-1, allows for a
Novel PET imaging agent detects earliest signs of Alzheimer's disease Read More »
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