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Researchers look to licorice for promising cancer treatments

Researchers look to licorice for promising cancer treatments

Licorice is more than a candy people either love or hate — it may play a role in preventing or treating certain types of cancer, according to researchers at the University of Illinois Chicago. Gnanasekar Munirathinam and his research team are studying substances derived from the licorice plant Glycyrrhiza glabra to determine if they could […]

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Novel therapeutic agents may reduce the oncogenesis of metastatic prostate cancer

Novel therapeutic agents may reduce the oncogenesis of metastatic prostate cancer

Researchers have found that treating prostate cancer cells with novel cyclin-dependent kinase 19 (CDK19) and homologous cyclin-dependent kinase 8 (CDK8) inhibitors reduces their potential to migrate into and invade surrounding structures. These molecules may be used as single or combination therapy for patients with advanced disease to prevent and treat metastatic spread. The results appear

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Less prostate cancer screening reduces overdiagnosis but may miss aggressive cases

Less prostate cancer screening reduces overdiagnosis but may miss aggressive cases

Over the past 15 years, public health authorities have downgraded recommendations for the prostate-specific antigen (PSA) test as a screening tool to reduce the overdiagnosis and overtreatment of men with low-grade prostate cancer. Now, researchers from Weill Cornell Medicine have found that while these efforts have been effective, the incidence of higher-grade disease and metastasis

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New combined therapy helps extend lives of men with prostate cancer

New combined therapy helps extend lives of men with prostate cancer

Practice-changing research from Cedars-Sinai Cancer shows that a combination of androgen deprivation therapy — a commonly used hormone injection — plus pelvic lymph node radiation, kept nearly 90% of clinical trial patients’ prostate cancer at bay for five years. The findings were published in the peer-reviewed journal The Lancet. The study also shows that patients

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Hormones contribute to sex disparities in bladder cancer, study shows

Hormones contribute to sex disparities in bladder cancer, study shows

Male sex hormones interfere with the body’s ability to fight bladder cancer, likely explaining why males experience higher cancer rates and more deadly disease, according to a new study co-led by a Cedars-Sinai Cancer investigator. These findings, published in Science Immunology, could represent a significant step toward unraveling why disparities in cancer incidence, prognosis and

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Novel PET imaging agent detects earliest signs of Alzheimer's disease

Novel PET imaging agent detects earliest signs of Alzheimer's disease

A new highly selective PET imaging agent can detect the presence of overexpressed monoamine oxidase-B (MAO-B) in cognitively unimpaired individuals with high beta amyloid (Ab) — one of the earliest signs of Alzheimer’s disease — according to research published in the October issue of The Journal of Nuclear Medicine. The radiotracer, 18F-SMBT-1, allows for a

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'Coolsculpting' inventors develop new non-surgical method for targeting fat

'Coolsculpting' inventors develop new non-surgical method for targeting fat

How cool is this: the Massachusetts General Hospital (MGH) laboratory that invented cryolipolisis or “Coolsculpting,” a popular non-surgical method for reducing fat under the skin, is developing a new form of the technology that can selectively reduce fat almost anywhere in the body using a safe, injectable ice solution or “slurry.” The technology, not yet

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