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Research into use of diabetes medication for treatment of metastatic prostate cancer

Research into use of diabetes medication for treatment of metastatic prostate cancer

Patients with localised prostate cancer have a good chance of survival, but mortality rates among those with advanced, metastatic forms of the condition remain high. Until now, the precise mechanism behind the spread of the tumour has not been fully explained. But an international research team headed by MedUni Vienna has succeeded in decoding the […]

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New insights into androgen's action could boost battle against prostate cancer

New insights into androgen's action could boost battle against prostate cancer

Researchers at UVA Cancer Center have unveiled important new insights into how hormones known as androgens act on our cells — and the discovery could boost efforts to develop better treatments for prostate, ovarian and breast cancers. The findings shed light on how androgens interact with their receptors inside cells to affect gene activity. This

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Anti-androgen therapy can fuel spread of bone tumors in advanced prostate cancer

Anti-androgen therapy can fuel spread of bone tumors in advanced prostate cancer

Dr Bock, under the mentorship of Distinguished Professor Dietmar Hutmacher, from QUT Centre for Biomedical Technologies, has focused her research on bone metastases from breast and prostate cancers. She developed 3D miniature bone-like tissue models in which 3D printed biomimetic scaffolds are seeded with patient-derived bone cells and tumour cells to be used as clinical

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Patients helping researchers to advance treatments for prostate cancer

Patients helping researchers to advance treatments for prostate cancer

Researchers at Monash University have established one of the world’s largest collections of living tumours from prostate cancer patients, accelerating the testing of new treatments for prostate cancer and leading to faster patient benefit. One of the most common cancers, prostate cancer is also one of the most difficult to study in the laboratory, with

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Staying young, from the cells on up

Staying young, from the cells on up

Researchers at Université de Montréal and McGill University have discovered a new multi-enzyme complex that reprograms metabolism and overcomes “cellular senescence,” when aging cells stop dividing. In their study published today in Molecular Cell, the researchers show that an enzyme complex named HTC (hydride transfer complex) can inhibit cells from aging. “HTC protects cells from

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Studies biased toward genomes of people with European ancestry still predict cancer risk in diverse groups, research finds

Studies biased toward genomes of people with European ancestry still predict cancer risk in diverse groups, research finds

Data sets that are biased by having too many genomes from people with European ancestry can still be applied to other ancestry groups to predict their risk of developing breast and prostate cancer. Lars Fritsche of the University of Michigan and colleagues report these findings in a new study published Sept. 16 in PLOS Genetics.

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Metastatic prostate cancer comes in two forms, which could guide treatment

Metastatic prostate cancer comes in two forms, which could guide treatment

Scientists have identified two subtypes of metastatic prostate cancer that respond differently to treatment, information that could one day guide physicians in treating patients with the therapies best suited to their disease. Building off of earlier studies that discovered clinically relevant subtypes of breast cancer and non-metastatic prostate cancer, researchers identified genetic signatures that can

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Research shows exercise-related proteins can suppress tumor growth

Research shows exercise-related proteins can suppress tumor growth

Forget bedrest, research from Edith Cowan University (ECU) has shown exercise may be a key weapon in cancer patients’ battle against the disease. Exercise causes muscles to secrete proteins called myokines into our blood — and researchers from ECU’s Exercise Medicine Research Institute have learned these myokines can suppress tumour growth and even help actively

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