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‘Gut bugs’ can drive prostate cancer growth and treatment resistance

‘Gut bugs’ can drive prostate cancer growth and treatment resistance

Common gut bacteria can fuel the growth of prostate cancers and allow them to evade the effects of treatment, a new study finds. Scientists revealed how gut bacteria contribute to the progression of advanced prostate cancers and their resistance to hormone therapy — by providing an alternative source of growth-promoting androgens, or male hormones. Hormone […]

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Targeted prostate cancer screening could benefit men with inherited cancer syndrome

Targeted prostate cancer screening could benefit men with inherited cancer syndrome

Men who inherit an increased risk of cancer through ‘Lynch syndrome’ could benefit from regular PSA testing from age 40 to detect early signs of prostate cancer, researchers believe. Lynch syndrome raises the risk of several cancer types including most famously bowel cancer, and affects 175,000 people in the UK — although only 5 per

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Study links gut microbiome and aggressive prostate cancer

Study links gut microbiome and aggressive prostate cancer

Cleveland Clinic researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, suggesting dietary interventions may help reduce risk. Findings from the study were published in Cancer Epidemiology, Biomarkers & Prevention. While more research will be necessary, the study’s lead author Nima Sharifi, M.D., says findings

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Prostate cancer urine test identifies good prognosis patients

Prostate cancer urine test identifies good prognosis patients

Researchers at the University of East Anglia have shown that a prostate cancer urine test can identify men at ‘intermediate risk’ who can safely avoid immediate treatment and benefit from ‘active surveillance’ instead. A new pilot study published today reveals how urine biomarkers can show the amount of significant cancer in a prostate, highlighting with

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New prostate cancer biomarkers provide hope to millions of men

New prostate cancer biomarkers provide hope to millions of men

University of South Australia researchers have identified three new biomarkers for prostate cancer to help identify and differentiate potentially aggressive cases of the disease which kills more than 300,000 men each year. An international team of scientists led by UniSA Professor of Molecular Medicine Doug Brooks has made the breakthrough, which assists pathologists when visualising

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New strategy against treatment-resistant prostate cancer identified

New strategy against treatment-resistant prostate cancer identified

Many patients with prostate cancer are treated with drugs that lower or block hormones that fuel tumor growth. While the drugs are effective for a time, most patients eventually develop resistance to these therapies. A new study from Washington University School of Medicine in St. Louis has identified an RNA molecule that suppresses prostate tumors.

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A step toward treating chemotherapy-resistant prostate cancer

A step toward treating chemotherapy-resistant prostate cancer

Prostate cancer is a leading cause of death among American men, and it’s resistant to one of the most powerful chemotherapy medications — cisplatin. Now, researchers reporting in ACS Central Science have developed the first therapy of its kind that disrupts prostate cancer cells’ metabolism and releases cisplatin into the weakened cells, causing them to

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Statin use affects prostate cancer screening results

Statin use affects prostate cancer screening results

Prostate cancer screening results differ in men taking cholesterol-lowering statin drugs compared with non-users, a study conducted at Tampere University in Finland finds. In statin users, screening did not increase the incidence of prostate cancer as it did in other men. The study found the clearest difference in low-risk cancer, which is often overdiagnosed due

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A step toward treating chemotherapy-resistant prostate cancer

MRI innovation makes cancerous tissue light up and easier to see

A new form of magnetic resonance imaging (MRI) that makes cancerous tissue glow in medical images could help doctors more accurately detect and track the progression of cancer over time. The innovation, developed by researchers at the University of Waterloo, creates images in which cancerous tissue appears to light up compared to healthy tissue, making

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